The Potential is Real – The Confusion is Overwhelming – The Passion is Blinding. So What do we do? Is sticking our heads in the sand of ignorance the right approach?
We wanted to explore what is going on in the intellectual property front of the embryonic stem cell landscape. This will provide insight into what the research and business enterprises focus in. it will shed light on directions, possibilities, and actualities.
Note though, that not all that’s patented is all that there is … for example the Geron Corporation is associated with only the following patents associated directly with embryonic stem cells.
Clearly, from title analysis, Mammalian Telomerase is a one of their major keys to the lock.
PAT. NO. Title 1 6,258,535 Mammalian telomerase 2 6,166,178 Telomerase catalytic subunit 3 6,147,276 Quiescent cell populations for nuclear transfer in the production of non-human mammals and non-human mammalian embryos 4 6,054,575 Mammalian telomerase RNA gene promoter 5 5,958,680 Mammalian telomerase 6 5,837,857 Mammalian telomerase 7 5,776,679 Assays for the DNA component of human telomerase 8 5,583,016 Mammalian telomerase
LISTING OF THE MOST CURRENT U.S. PATENTS on EMBRYONIC STEM CELLS
PATENT # Title 6,274,363 Phosphatidylcholine phospholipase D 6,274,362 RGS-containing molecules and uses thereof 6,274,338 Human c-Maf compositions and methods of use thereof 6,274,309 Method for the modulation of acid-sphingomyelinase-related apoptosis 6,271,436 Cells and methods for the generation of transgenic pigs 6,271,348 Tetracycline-inducible transcriptional inhibitor fusion proteins 6,271,341 Transcriptional activators with graded transactivation potential 6,270,778 Melanoma antigens and their use in diagnostic and therapeutic methods 6,268,135 Phospholipase molecule and uses therefor 6,268,130 RP compositions and diagnostic uses therefor 6,265,564 Expressed ligand-vascular intercellular signalling molecule 6,265,546 Prostate cancer gene 6,262,337 Transgenic animal with recombinant vascular endothelial growth factor B (VEGF-B DNA) and uses thereof 6,262,235 Leptospiral outer membranes protein, LipL46 6,262,035 Gene replacement therapy for muscular dystrophy 6,261,818 CARK protein and nucleic acid molecules and uses therefor 6,258,998 Method of cloning porcine animals 6,258,582 CSAPTP nucleic acid molecules and uses therefor 6,258,557 Smooth muscle cell LIM promoter 6,258,535 Mammalian telomerase 6,255,473 Presenilin-1 gene promoter 6,255,458 High affinity human antibodies and human antibodies against digoxin 6,255,112 Regulation of hematopoietic stem cell differentiation by the use of human mesenchymal stem cells 6,252,136 Transgenic organisms having tetracycline-regulated transcriptional regulatory systems 6,252,132 Mutant mouse containing a knockout mutation in DNA encoding an endogenous alpha 4 subunit of nicotinic acetylcholine receptor 6,252,051 ErbB4 receptor-specific neuregulin related ligand antibodies and uses therefor 6,251,671 Compositions and methods of making embryonic stem cells 6,248,934 Gene trap vectors 6,248,527 Method of detecting risk of type II diabetes based on mutations found in carboxypeptidase E 6,245,969 Receptor kinase, Bin1 6,245,566 Human embryonic germ cell line and methods of use 6,245,529 Testis-specific cystatin-like protein cystatin T 6,245,527 Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof 6,242,667 Transgenic organisms having tetracycline-regulated transcriptional regulatory porno mexicano systems 6,242,588 Testis specific glycoprotein zpep10 6 6,242,236 Method of promoting enzyme diversity 6,239,326 Sparc-deficient transgenic mice 6,238,903 SH2-containing inositol-phosphatase 6,238,881 Nucleic acids and polypeptides related to a guanine exchange factor of Rho GTPase