The University of Manchester

Oxford Road
Manchester M13 9PT
UK

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The University of Manchester, formed in 2004 from the merger of two premier Universities, is the
largest in the UK (annual turnover of almost 1bn Euros), and recognised for strength in research.
In the last national exercise it gained the top scores for research in biology and pre-clinical
medicine. It has outstanding facilities, most notably those relevant to the proposal e.g.
animal facilities (including transgenics), imaging, molecular and cell biology and close links with
medicine, where it has one of the highest incidences and largest catchment areas for stroke
patients in Europe.

Prof. Nancy Rothwell’s group is a leading research group in neuroinflammation (>20 research
members) spanning basic cellular, physiology and clinical approaches. They receive extensive
external funding (Eu 5M) and have over 40 PhD students trained. They benefit from extensive
institutional support and unique facilities (leading life sciences grouping with top, 5*,
ranking at last UK national assessment).

The team leader, Prof. Nancy Rothwell has approx. 400 publications and currently holds
over 5M Euros in external peer reviewed grants, most are focused on stroke, from basic
mechanisms to clinical applications. She is a Fellow of the Royal Society (one of the worlds
premier scientific academies), has extensive experience of leadership in research funding
(chair of many major funding panels and Council member of leading funding bodies), has trained
approximately 40 PhD students and her clinical research has been recognised by the rare honour
(for a scientist) of honorary fellowship of the Royal College of Physicians. She has many other
national and international awards.

Role in Project

The University of Manchester (UNIMAN) is the leader of WP02 and is involved in WPs
03, 07, 08 and 10. Our key tasks are to determine: the role of systemic inflammation/infection
in stroke, the link between validated pathways in new models, clinically relevant biomarkers
of (risk of) stroke, new therapeutic targets.

Project Leader

Prof. Nancy Rothwell Phone: +44 161 275 5357 Fax: +44 161 275 5948 Contact

Project Staff

Dr Stuart Allan Role in overall research direction; expertise in anti-inflammatory treatments and systemic inflammation Tel. +44 161 275 5255 Contact