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ADVANCE: STEM CELL FIGHTS MULTIPLE SCLEROSIS

Posted on January 28, 2023by admin

For more than two decades, stem cells have been sold in the media, cinema and television as a magical solution that opens the doors in medicine. However, those who enter more on the subject, do not take long to realize that their uses are, in a certain way, limited.

According to the International stem cell research society, there are still very few studies with favorable results where stem cells are used to meet diseases.

However, recent studies suggest that, precisely stem cells could mean an opportunity for those who suffer from multiple sclerosis.

HOW DOES MULTIPLE SCLEROSIS WORK?

In countries such as Denmark, Sweden, Hungary and Cyprus, statistically known for being those with more volume of cases, 1 in 300 people suffer from multiple sclerosis. In many of these cases, this disease derives in disability or reduced mobility, due to its aggressive attack on the nervous system.

Due to a disorder in the behavior of autoimmune cells, the organism attacks the myelin that covers each neuron, affecting communication between the brain and the rest of systems, organs and other tissues that make up the human body.

A NEW STUDY DESIGNED G¡FOR ACUTE CASES

At the beginning of 2023, the American Academy of Neurology published through its magazine ‘Neurology’ an Italian study where the use of stem cells in patients with progressive secondary multiple sclerosis was studied.

These types of patients, like others affected by the disease, are characterized by outbreaks and remissions of aggressive symptoms video porno, deriving in medium or long -term disability.

The study consisted of the injection of blood cells of a healthy body in the patient’s body, as a measure to replace sick cells.

HOW DID THE STUDY BE CARRIED OUT?

To perform the experiment, a retrospective analysis of 79 cases of active progressive secondary sclerosis was carried out. Each received a stem cell transplant, and then compare the behavior of the disease with a database of 1975 patients with similar pictures, but treated with drugs.

The two groups were segmented by age, sex and degree of disability, and each patient was assigned a score from 0 to 10, according to the expanded scale of the state of disability. Subsequently, the progress of his illness was studied in a period of 10 years.

HOW DID THE STUDY BE CARRIED OUT? — (Pexel)

At the beginning of the study, the average punctuation of the patients was 6.5, in need of moving using orthopedic or cane apparatus. However, over time, considerable improvement was observed in indicators for patients undergoing stem cell treatment.

ANALYSIS OF RESULTS

When performing an analysis of the cases, it could be concluded that the use of stem cells began to progressively reduce the progress of the disease in patients, allowing them an extension in their quality of life. The measure was, in numerous cases, much more effective than the use of conventional multiple sclerosis.

Although long -cell treatment with stem cells for this disease has already been considered effective, until then it had only been tested with more premature states of it. However, the treatment was effective even in patients with more serious and advanced paintings.

Without a doubt, this represents a hope for patients who, for one reason, handle an acute picture of the disease.

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STEM CELLS AGAINST HAIR LOSS

Posted on August 7, 2022by leonardo

STEM CELLS AGAINST HAIR LOSS

We know it’s terrifying: brushing your hair while watching the strands fall out of control one by one. We also know that, even many times, the fact of not being able to stop this condition immediately generates the stress that produces a more accelerated fall.

So don’t worry, today that we have come to talk about alopecia, we understand how important it is for those who suffer from it to find a quick and effective solution. Fortunately for many, there are currently numerous treatments to deal with this condition. One of the most effective involves the use of stem cells.

BUT WHY DOES HAIR FALL OUT?

Before talking about the solution, we should be clear about why, in the beginning, hair loss appears. We would like to have a direct and precise answer. However, there are many reasons, so we will try to give you a brief summary of the most common ones. Maybe you will find one that you identify with.

The first thing you should know is that, just like animal fur, humans also “shed” their hair seasonally. Let’s remember that the hair production process is cyclical, and therefore, it is natural that at certain times of the year your hair falls out periodically porno français.

When to start worrying? When you notice that this fall is permanent, that it does not stop or lighten over time. If this is the case, you should pay attention to these external factors:
• Stress.
• A diet that is too strict.
• Abuse of irons, dyes or other aggressive treatment on the hair.

The good news in these cases is that, naturally, a change in habits can help you gradually stop hair loss.
However, when we talk about causes more associated with the biological, such as hormonal changes, aging or diseases such as COVID-19, it is best to seek a professional medical opinion.

TREATING BALDNESS WITH STEM CELLS

Stem cells today seem to be the answer that medicine has been looking for for years. A biological substance capable of forcing the regeneration of tissues in a natural and minimally invasive way, in addition to the absence of terrible consequences for those who use them.

Especially with hair loss, there are already many treatments that can be seen on the market. After all, these cells stimulate the birth of new cells that form tissues that, in turn, strengthen the scalp.

TREATING BALDNESS WITH STEM CELLS

Stem cell treatments to attack alopecia or extreme hair loss are varied and come in numerous presentations: shampoos, scrubs, oils, capsules, masks, sprays, serums, etc.

When choosing one, we recommend that you read its prescription. Each brand usually has a guide of which format to use, depending on the cause that drives your hair loss.

And you, what brought you to the end of this note? Do you suffer from alopecia? Tell us about your experience in the comments or share with a friend who really needs the information.

Opinions

Is compression ultrasound sufficient for diagnosing deep vein thromboses in the outpatient arena?

Posted on October 3, 2018by admin

Clinical Bottom Lines:

1. Ultrasound with a follow-up study between 5 and 7 days, after the initial test, makes a bad outcome in patients with potential DVTs very unlikely. Much of this risk relates to the prevalence of the condition.

2. If there is high suspicion of a clot as a result of known predisposing factors then the diagnosis needs to be pursued with more vigor.

The Method/Evidence:

Consecutive outpatients were determined to have a normal or abnormal scan.

If abnormal the patients had a venogram, and if this was not done, they were started on heparin.

If the scan was normal, it was repeated 5 to 7 days later.

End points were death, or thromboembolic event.

Exclusions: if compression ultrasonography could not be done or there were technical limitations, follow-up was not assured, the patient had received therapeutic doses of heparin for more than 24 hours, or if the patient was pregnant.

Patients were followed up to 3 months after initial contact.

The negative likelihood ratio of no bad outcome after two negative tests is 2/6 divided by 333/397=0.397

Comments:

1. Although this article did not address sensitivities and specificities, since a gold standard was not used for all patients, it did address a more important issue. What is the chance of having a bad event if your scans are negative? The answer looks like it’s very low. The reason it’s low is that the prevalence is low. This is why although the numbers look impressive the calculated likelihood ratios are not that impressive.

2. The researchers intentionally did not include a gold standard for negative tests because they wanted to see what the long term results would be if the patients were not treated. If they had obtained a venogram which showed clot it probably would have been unethical to withhold treatment. Unfortunately it is difficult to know if patients did well because the chances of a bad outcome were so low to start or for another reason.

3. The study probably needed more patients so that there were more events.

4. Although I would feel comfortable withholding heparin for a normal person, if your suspicion for clot is high secondary to known predisposing factors, eg cancer, lupus…, then you probably need to pursue the diagnosis more.

5. The study is actually good, but it depends on the prevalence of the disease.

Source:

Birdwell BG, Raskob GE, Whitsett TL, Durica SS, Comp PC, George JN, Tytle TL and McKee PA. The Clinical Validity of Normal Compression Ultrasonography in Outpatients Suspected of Having Deep Venous Thrombosis. Annals of Internal Medicine 1998: 128:1 1-7.